Species-specific urokinase receptor ligands reduce glioma growth and increase survival primarily by an antiangiogenesis mechanism (Q40565134)

21 September 2017

title

Species-specific urokinase receptor ligands reduce glioma growth and increase survival primarily by an antiangiogenesis mechanism (English)

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21 September 2017

Xingyao Bu

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21 September 2017

Vazgen Khankaldyyan

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21 September 2017

Ignacio Gonzales-Gomez

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21 September 2017

Susan Groshen

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21 September 2017

Wei Ye

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21 September 2017

Shaoqiu Zhuo

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21 September 2017

Jaume Pons

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21 September 2017

Jennifer R Stratton

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21 September 2017

Steven Rosenberg

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21 September 2017

Walter E Laug

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21 September 2017

publication date

1 June 2004

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21 September 2017

published in

Laboratory Investigation

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21 September 2017

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21 September 2017

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21 September 2017

page(s)

667-678

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The plasminogen activation system in tumor growth, invasion, and metastasis

21 September 2017

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Randomized adjuvant chemotherapy trial in high-risk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1.

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Regulation of integrin function by the urokinase receptor

21 January 2018

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Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice

21 January 2018

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Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

21 January 2018

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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

21 January 2018

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Nonproteolytic role for the urokinase receptor in cellular migration in vivo

21 January 2018

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Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors

21 January 2018

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Yeast expression and phagemid display of the human urokinase plasminogen activator epidermal growth factor-like domain

21 January 2018

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Selective expression of adhesion molecules on human brain microvascular endothelial cells

21 January 2018

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High-affinity urokinase receptor antagonists identified with bacteriophage peptide display

21 January 2018

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Role and localization of urokinase receptor in the formation of new microvascular structures in fibrin matrices

21 January 2018

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Determination of the proliferation and apoptotic index in adrenocorticotropin-secreting pituitary tumors : comparison between micro- and macroadenomas

21 January 2018

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Systemic delivery of antiangiogenic adenovirus AdmATF induces liver resistance to metastasis and prolongs survival of mice

21 January 2018

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Urokinase induces receptor mediated brain tumor cell migration and invasion.

21 January 2018

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Expression and cellular localization of low-density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor in human glioblastoma in vivo

21 January 2018

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Polyoma middle T-induced vascular tumor formation: the role of the plasminogen activator/plasmin system

21 January 2018

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uPAR: a versatile signalling orchestrator

21 January 2018

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alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin

21 January 2018

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The chemotactic action of urokinase on smooth muscle cells is dependent on its kringle domain. Characterization of interactions and contribution to chemotaxis

21 January 2018

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Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration

21 January 2018

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Integrin activation takes shape

21 January 2018

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

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The kringle stabilizes urokinase binding to the urokinase receptor

21 January 2018

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Drug and gene targeting to the brain with molecular Trojan horses

21 January 2018

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Clinical translation of angiogenesis inhibitors

21 January 2018

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Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy

21 January 2018

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Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences

21 January 2018

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Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection

21 January 2018

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Urokinase receptor antagonists: discovery and application to in vivo models of tumor growth.

21 January 2018

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7 January 2021

Urokinase plasminogen activator is localized in stromal cells in ductal breast cancer

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7 January 2021

Binding of Human Urokinase-Type Plasminogen Activator to Its Receptor

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7 January 2021

Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins

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7 January 2021

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

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7 January 2021

The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling

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7 January 2021

Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients

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7 January 2021

Plasminogen promotes sarcoma growth and suppresses the accumulation of tumor-infiltrating macrophages

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7 January 2021

PAI-1 inhibits urokinase-induced chemotaxis by internalizing the urokinase receptor

1 reference

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7 January 2021

10.1038/LABINVEST.3700089

Identifiers

DOI

1 reference

Dimensions Publication ID

21 September 2017

1005030854

0 references

1 reference