APE1/Ref-1 regulates PTEN expression mediated by Egr-1 (Q24650473)

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Carlo Vascotto

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Marta Deganuto

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Nicoletta Bivi

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Gabriella Marcon

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Franco Quadrifoglio

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Giuseppe Damante

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Kishor K Bhakat

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Sankar Mitra

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

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language of work or name

English

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publication date

January 2008

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published in

Free Radical Research

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volume

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issue

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page(s)

20-9

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cites work

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Regulation of PTEN transcription by p53

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Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo.

28 September 2017

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Down-regulation of apurinic/apyrimidinic endonuclease expression is associated with the induction of apoptosis in differentiating myeloid leukemia cells.

28 September 2017

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Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity

28 September 2017

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Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN.

28 September 2017

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Suppression of growth and transformation and induction of apoptosis by EGR-1.

30 May 2018

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30 May 2018

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Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism

30 May 2018

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Suppression of v-sis-dependent transformation by the transcription factor, Egr-1.

30 May 2018

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Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein.

30 May 2018

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The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

21 January 2018

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https://api.crossref.org/works/10.1080%2F10715760701765616

Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution

21 January 2018

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Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18324520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Redox factor 1 (Ref-1) enhances specific DNA binding of p53 by promoting p53 tetramerization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18324520