Targeted transgenesis (Q24631266)

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Language	Label	Description	Also known as
English	Targeted transgenesis	scientific article

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scholarly article

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Targeted transgenesis (English)

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author name string

M Jasin

1

author given names

M

author last names

Jasin

1 reference

PubMed publication ID

19 October 2023

M E Moynahan

2

author given names

M E

author last names

Moynahan

1 reference

PubMed publication ID

19 October 2023

C Richardson

3

author given names

C

author last names

Richardson

1 reference

PubMed publication ID

19 October 2023

language of work or name

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publication date

20 August 1996

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Proceedings of the National Academy of Sciences of the United States of America

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93

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17

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8804-8

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Chromosomal double-strand break repair in Ku80-deficient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Genetic transformation of mouse embryos by microinjection of purified DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Heterologous introns can enhance expression of transgenes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Establishment in culture of pluripotential cells from mouse embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Genetic manipulation of genomes with rare-cutting endonucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

7 April 2017

Single-copy transgenic mice with chosen-site integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Diverse strategies for tetracycline-regulated inducible gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Relationship between asymmetric nodal expression and the direction of embryonic turning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Mouse limb muscle is determined in the absence of the earliest myogenic factor myf-5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

The 5' flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Targeting the mouse genome: a compendium of knockouts (part II)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Chromosome engineering in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Introduction of a rabbit beta-globin gene into the mouse germ line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Transgenesis by means of blastocyst-derived embryonic stem cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Effects of the position of the simian virus 40 enhancer on expression of multiple transcription units in a single plasmid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Targeted replacement of the homeobox gene Hox-3.1 by the Escherichia coli lacZ in mouse chimeric embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

27 September 2017

Expression of the lacZ gene targeted to the HPRT locus in embryonic stem cells and their derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

30 May 2018

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

30 May 2018

Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

30 May 2018

Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

30 May 2018

Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

30 May 2018

Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

30 May 2018

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38547

28 November 2018

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homologous integration in mammalian cells without target gene selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the mouse genome: a compendium of knockouts (part III)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential function of LIF receptor in motor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of transgene expression to the vascular endothelium of mice by homologous recombination at the thrombomodulin locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799106

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.93.17.8804

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1996PNAS...93.8804J

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PubMed publication ID

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