The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis. (Q39281417)

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12 February 2020

title

The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis (English)

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12 February 2020

Weijuan Shao

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12 February 2020

Dingyan Wang

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Yu-Ting Chiang

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Wilfred Ip

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Lingyun Zhu

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12 February 2020

Fenghao Xu

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12 February 2020

Joshua Columbus

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Denise D Belsham

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12 February 2020

Haibo Zhang

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12 February 2020

Qinghua Wang

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12 February 2020

Tianru Jin

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language of work or name

English

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publication date

10 September 2012

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12 February 2020

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volume

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issue

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page(s)

789-800

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

12 February 2020

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyrighted

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cites work

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

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10 September 2017

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10 September 2017

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Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

10 September 2017

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Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

10 September 2017

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10 September 2017

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10 September 2017

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TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism

10 September 2017

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Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

10 September 2017

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P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine

10 September 2017

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Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells

14 September 2017

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Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

14 September 2017

1 reference

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Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

14 September 2017

1 reference

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Generation of a Phenotypic Array of Hypothalamic Neuronal Cell Models to Study Complex Neuroendocrine Disorders

14 September 2017

1 reference

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Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells

14 September 2017

1 reference

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Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line

14 September 2017

1 reference

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Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice

25 September 2017

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Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system

17 June 2018

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Glucagon gene 5'-flanking sequences direct expression of simian virus 40 large T antigen to the intestine, producing carcinoma of the large bowel in transgenic mice

17 June 2018

1 reference

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Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 [corrected](NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice.

17 June 2018

1 reference

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Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581223

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581223

Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581223

Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581223

Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581223

A glucagon-like peptide-1 receptor agonist and an antagonist modify macronutrient selection by rats

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22966074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB12-0365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966074%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966074%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

22966074

1 reference

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