Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Jun;98(24):e16001.
doi: 10.1097/MD.0000000000016001.

Peritoneal sarcoidosis: A case report

Seung Wook Lee  1 , Min Hee Lee  1 , Ji Eun Lee  1 , Seo Youn Choi  1 , Boem Ha Yi  1 , Jung Min Jung  2
Affiliations
Case Reports

Peritoneal sarcoidosis: A case report

Seung Wook Lee et al. Medicine (Baltimore). 2019 Jun.

Abstract

Rationale: Sarcoidosis is an idiopathic granulomatous disease. Although the lungs are most commonly involved, any organ may be affected. To assist with future diagnoses, we describe a rare case of peritoneal sarcoidosis in a young female patient, and present a literature review.

Patient concerns: A 32-year-old female patient presented to our institution with abdominal discomfort. She was evaluated with contrast-enhanced abdominal computed tomography (CT), and multiple enlarged lymph nodes were detected at the hepatic artery and left gastric artery nodal stations. The patient was lost during follow-up, but returned after 7 months and again underwent abdominal CT. This revealed diffuse nodular thickening of the peritoneum and the appearance of omental cake in her abdomen.

Diagnosis: Excisional biopsy of a lymph node was performed and extrapulmonary sarcoidosis was confirmed.

Interventions: The patient was treated with corticosteroid.

Outcomes: A follow-up abdominal CT scan after two weeks revealed decreases in the numbers and sizes of the previously enlarged lymph nodes, and improvement in the ascites and peritoneal thickening.

Lessions: Peritoneal sarcoidosis should be considered as an additional differential diagnosis when peritoneal carcinomatosis or tuberculous peritonitis are suspected. In this regard, serum levels of angiotensin-converting enzyme (ACE) may be a valuable diagnostic indicator of unusual sarcoidosis presentations.

PubMed Disclaimer

Conflict of interest statement

Seung Wook Lee, Ji Eun Lee, Seo Youn Choi, Boem Ha Yi, and Jung Min Jung declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
(A) A lymph node along the hepatic artery is approximately 2 cm in diameter and shows central low density on a contrast enhanced CT scan. (B) The lymph node shows strong 18F-FDG uptake on a PET-CT.
Figure 2
Figure 2
(A) On axial and (B) coronal reformatted CT images of a contrast enhanced CT scan performed 7 months later shows significant aggravation of the lymphadenopathy of the porta hepatis, development of diffuse nodular thickening of the peritoneum and ascites.
Figure 3
Figure 3
Lymph node shows capsular fibrosis and numerous granulomas. Granulomas are composed of epithelioid histiocytes and surrounded by a rim of lymphocytes (A. H&E, ×100). In some granulomas, central foci of fibrinoid necrosis is observed (B. H&E, ×200).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Baughman RP, Lower EE, Gibson K. Pulmonary manifestations of sarcoidosis. Presse Med 2012;41(6 Pt 2):e289–302. - PubMed
    1. Gorkem U, Gungor T, Bas Y, et al. Abdominal sarcoidosis may mimic peritoneal carcinomatosis. Case Rep Obstet Gynecol 2015;2015:263945. - PMC - PubMed
    1. Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis. New Engl J Med 2007;357:2153–65. - PubMed
    1. Bernaciak J, Spina JC, Curros ML, et al. Case report: peritoneal sarcoidosis in an unusual location. Semin Respir Crit Care Med 2002;23:597–600. - PubMed
    1. Warshauer DM, Lee JK. Imaging manifestations of abdominal sarcoidosis. Am J Roentgenol 2004;182:15–28. - PubMed

Publication types

Substances