New student Cady Heron is welcomed into the top of the social food chain by the elite group of popular girls called “The Plastics,” ruled by the conniving queen bee Regina George in Tina Fey's new twist on the modern classic, MEAN GIRLS.

Emma (Kaley Cuoco) and Dave (David Oyelowo) spice up their wedding anniversary with a night of role-play in New York City. But things turn perilous when Emma's secret life as an international assassin, unknown to Dave, is exposed by Bob (Bill Nighy), jeopardizing her family. Emma must rely on her lethal skills and determination to protect her family at all costs.