Broad-spectrum antibiotics were initially used to fight a bacterial infection released by the Silurians in the 20th century, until the Third Doctor and Liz Shaw had concocted an effective antidote. (TV: Doctor Who and the Silurians)

In the early 2020s, the equipment at Suki Cheng's laboratory included broad-spectrum antibiotics. The Thirteenth Doctor needed them to examine the Praxeus pathogen. (TV: Praxeus)