(Q40146414)

17 September 2017

title

Identification of novel Wilms' tumor suppressor gene target genes implicated in kidney development (English)

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17 September 2017

Karim Malik

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Ho-Shik Kim

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17 September 2017

Myoung Shin Kim

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17 September 2017

Anne L Hancock

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17 September 2017

James C P Harper

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17 September 2017

Jik Young Park

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17 September 2017

George Poy

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17 September 2017

Alan O Perantoni

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17 September 2017

Margaret Cam

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17 September 2017

Sean Bong Lee

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17 September 2017

language of work or name

English

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publication date

12 April 2007

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Journal of Biological Chemistry

17 September 2017

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inferred from page(s)

published in

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17 September 2017

volume

282

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17 September 2017

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17 September 2017

page(s)

16278-16287

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Wilms' tumour gene and function

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Wilms' tumour: connecting tumorigenesis and organ development in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

WT-1 is required for early kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The Wilms tumor suppressor gene wt1 is required for development of the spleen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The Wilms' tumor gene Wt1 is required for normal development of the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Wilms tumor and the WT1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

21 January 2018

The complex life of WT1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Transcriptional regulation by WT1 in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Alternative splicing and genomic structure of the Wilms tumor gene WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

A mammal-specific exon of WT1 is not required for development or fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Analysis of WT1 target gene expression in stably transfected cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The human sex-determining gene SRY is a direct target of WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

E-cadherin is a WT1 target gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

WT1 regulates the expression of the major glomerular podocyte membrane protein Podocalyxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

WT1 induces apoptosis through transcriptional regulation of the proapoptotic Bcl-2 family member Bak.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Induction of tubules in rat metanephrogenic mesenchyme in the absence of an inductive tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Identification of connective tissue growth factor as a target of WT1 transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Functional characterization of WT1 binding sites within the human vitamin D receptor gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Anlaysis of complementary expression profiles following WT1 induction versus repression reveals the cholesterol/fatty acid synthetic pathways as a possible major target of WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Vascular endothelial growth factor (VEGF) is suppressed in WT1-transfected LNCaP cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Role of membrane-bound heparin-binding epidermal growth factor-like growth factor (HB-EGF) in renal epithelial cell branching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Fractalkine reduces N-methyl-d-aspartate-induced calcium flux and apoptosis in human neurons through extracellular signal-regulated kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Slug mRNA is expressed by specific mesodermal derivatives during rodent organogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Human Slug is a repressor that localizes to sites of active transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700215200

21 January 2018

Identifiers

DOI

10.1074/JBC.M700215200

1 reference

17 September 2017

1 reference