(Q34424004)

2 August 2017

title

Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analogues (English)

1 reference

2 August 2017

Conformational Dynamics in Human Purine Nucleoside Phosphorylase with Reactants and Transition-State Analogues (English)

1 reference

31 July 2024

Vern L Schramm

1 reference

2 August 2017

Jennifer S Hirschi

1 reference

2 August 2017

Karunesh Arora

1 reference

2 August 2017

Charles L. Brooks

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

31 July 2024

language of work or name

English

0 references

publication date

11 October 2010

1 reference

full work available at URL

2 August 2017

https://europepmc.org/articles/pmc3005859?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20936808/pdf/?tool=EBI

31 July 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20936808/?tool=EBI

31 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

https://europepmc.org/articles/PMC3005859

31 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

https://europepmc.org/articles/PMC3005859?pdf=render

31 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

https://doi.org/10.1021/jp108056s

31 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20936808

https://pubs.acs.org/doi/pdf/10.1021/jp108056s

31 July 2024

1 reference

Journal of Physical Chemistry B

31 July 2024

published in

1 reference

2 August 2017

volume

114

1 reference

2 August 2017

1 reference

2 August 2017

page(s)

16263-16272

1 reference

All-atom empirical potential for molecular modeling and dynamics studies of proteins

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Four generations of transition-state analogues for human purine nucleoside phosphorylase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Enzymatic transition states and dynamic motion in barrier crossing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields

6 July 2018

1 reference

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CHARMM: the biomolecular simulation program

6 July 2018

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Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Loop-tryptophan human purine nucleoside phosphorylase reveals submillisecond protein dynamics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Atomic detail of chemical transformation at the transition state of an enzymatic reaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Remote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Binding isotope effects: boon and bane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Enzymatic transition state theory and transition state analogue design

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Purine nucleoside phosphorylase. 1. Structure-function studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Improved treatment of the protein backbone in empirical force fields.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Polar hydrogen positions in proteins: Empirical energy placement and neutron diffraction comparison

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005859

Comparison of simple potential functions for simulating liquid water

27 October 2018

1 reference

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

31 July 2024

1 reference

Finite representation of an infinite bulk system: Solvent boundary potential for computer simulations

31 July 2024

1 reference

31 July 2024

Identifiers

DOI

10.1021/JP108056S

1 reference

2 August 2017

1 reference

2 August 2017

1 reference