(Q34391393)

1 August 2017

title

Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease (English)

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1 August 2017

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H E Stanley

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1 August 2017

B Urbanc

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1 August 2017

L Cruz

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1 August 2017

R Le

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1 August 2017

J Sanders

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1 August 2017

K Hsiao Ashe

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1 August 2017

K Duff

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1 August 2017

M C Irizarry

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1 August 2017

B T Hyman

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1 August 2017

language of work or name

English

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publication date

9 October 2002

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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inferred from page(s)

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

13990-13995

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Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis.

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

6 July 2018

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Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

6 July 2018

1 reference

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6 July 2018

1 reference

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Description of microcolumnar ensembles in association cortex and their disruption in Alzheimer and Lewy body dementias

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Mechanisms of neuronal degeneration in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Alzheimer's disease: a central role for amyloid

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Methodological variables in the assessment of beta amyloid neurotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Amyloid (Abeta) deposition in chromosome 1-linked Alzheimer's disease: the Volga German families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137824

Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Neuron loss in APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

Abeta associated neuropil changes: correlation with neuronal loss and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222433299

21 January 2018

Identifiers

DOI

10.1073/PNAS.222433299

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1 August 2017

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1 August 2017

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