File:Formation of extraembryonic endoderm in mouse development.png
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| Description | Figure 3. Formation of extraembryonic endoderm in mouse development. Cells of the inner cell mass (yellow), expressing Oct4, Gata6 and Nanog, and those of the trophectoderm (grey), expressing Cdx2, are the primary cell populations present prior to implantation of the blastocyst. A second round of segregation leads to cells of the epiblast (red), which continue to express Nanog and will eventually give rise to the three germ layers of the embryo proper, and those committed towards the extraembryonic endoderm lineage that express Gata4 and 6, Sox7 and 17, Dab2 and FoxA2. Soon after, cells of the primitive extraembryonic endoderm that undergo an epithelial-to-mesenchymal transition, migrate on a basement membrane along the trophectoderm and develop as parietal extraembryonic endoderm (green). Primitive endoderm cells still associated with the basement membrane of the epiblast acquire a cuboidal morphology, and develop into visceral extraembryonic endoderm (purple); some of which contributes to definitive endoderm. |
| Date | |
| Source | https://www.mdpi.com/2221-3759/3/2/25 Kelly, G.M.; Drysdale, T.A. Retinoic Acid and the Development of the Endoderm. J. Dev. Biol. 2015, 3, 25-56. https://doi.org/10.3390/jdb3020025 |
| Author | Kelly, G.M.; Drysdale, T.A |
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© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 17:06, 2 September 2024 | | 2,262 × 1,908 (1.16 MB) | Rasbak (talk | contribs) | {{Information |description=Figure 3. Formation of extraembryonic endoderm in mouse development. Cells of the inner cell mass (yellow), expressing Oct4, Gata6 and Nanog, and those of the trophectoderm (grey), expressing Cdx2, are the primary cell populations present prior to implantation of the blastocyst. A second round of segregation leads to cells of the epiblast (red), which continue to express Nanog and will eventually give rise to the three germ layers of the embryo proper, and those com... |
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